Yes, the organism is not destroyed by formaldehyde, phenol, gluteraldehyde, alcohol, dry heat, boiling, hydrogen peroxide, ultraviolet radiation, or standard gravity sterilization.

The only effective sterilization technique is steam pressure sterilization (a process not commonly available to most funeral homes). However, even this method is not foolproof. In 2001 a major hospital in Denver reported the exposure of CJD to 6 neurosurgery patients as a result of the use of CJD contaminated surgical instruments after autoclaving. As a result they have changed their procedure to include disposal of all surgical instruments used on a known or suspected CJD patient. Other medical centers are known to double autoclave these surgical instruments. Incineration, is also effective but obviously destroys equipment along with the organism.

The use of sodium hypochlorite (household bleach) is often mentioned as a potential disinfectant, but its results are inconsistent. It is highly corrosive to metal instruments, gives off irritating fumes, and can not be used as an embalming agent.³⁴ For maximum effectiveness, soaking for two hours is recommended. Wiping floors or countertops with bleach, therefore would not produce this level of disinfection.

Sodium hydroxide (lye) is also mentioned as a disinfectant, but has also shown inconsistent results and is also corrosive. In addition, it is a hazardous substance itself which must be neutralized prior to disposal thus raising OSHA and EPA concerns for handling and disposal. Finally, it deteriorates with age, so it loses whatever effectiveness it may have while in storage.³⁵

Finally, it has been shown that the disease organism has long-term survivability. It is still viable and can be transmitted after an inactive period of a year or more.³⁶

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